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    (2018-01-01) CYP17 inhibitor abiraterone acetate as a promising future treatment for canine Cushing’s syndrome: in vitro investigations
    Wit, W.L. de
    INTRODUCTION: Cushing’s syndrome or hypercortisolism is one of the most frequently diagnosed endocrinopathies in dogs. At present, medical management of canine hypercortisolism consists of either trilostane or mitotane. Both treatments have disadvantages associated with undesired hypoadrenocorticism. Therefore, a more specific inhibition of cortisol production is desirable. The steroidogenic enzyme cytochrome P-450c17 (CYP17) could be an interesting target for selective inhibition of cortisol ....................
    (2018-01-01) Barriers veterinarians experience while discssing a dog's overweight.
    Aldewereld, C.M.
    During a randomized pilot study, it was found that veterinarians find it difficult to discuss overweight. Thus, the main question for this study arose: What are barriers and motivators for veterinarians to discuss a dog’s overweight. Sub hypotheses were formed based on literature to investigate if lack of time, fear of offending patients and lack of skills are potential barriers and if feeling responsible and feeling compassion are potential motivators for the veterinarian to discuss overweigh....................
    (2018-01-01) De Romanisering in de civitas Batavorum
    Boer, M. de
    Voor deze scriptie is onderzoek gedaan naar de Romanisering in de civitas Batavorum. Met behulp van het model van Chris Gosden, dat onder andere gebaseerd is op postkoloniale theorie, wordt er voorzien in de behoefte van nieuw en dynamisch onderzoek naar de complexe interactie in de grensgebieden. In dit onderzoek is geanalyseerd of de Romanisering in het leefgebied van de Bataven, op basis van de archeologische vondsten, te identificeren is als een praktijkvoorbeeld van de middle ground. Daarbi....................
    (2018-01-01) An Empirical Analysis of Evolutionary Particle Swarm Optimization
    Hoek, J. van
    Evolutionary Particle Swarm Optimization (EPSO) is a combination of Classic Particle Swarm Optimization and Evolutionary Algorithms. In this thesis we recreate the original EPSO algorithm and analyze its performance. Furthermore we extend the algorithm with uniform recombination, another idea from Evolutionary Algorithms. Finally we analyze why EPSO performs so well, and whether our extension fixes the mistakes made by EPSO or not.
    (2018-01-01) The Brokers, Colonial Mimicry, and Unattainable Trust: Agricultural Knowledge in the Dutch East Indies (1900s-1930s)
    Irawan Santoso Suryo Basuki, .
    This thesis would like to investigate how the agricultural knowledge was produced and circulated in the Dutch East Indies in the Ethical Policy period (1901-1942). It argues that, in the beginning, knowledge provided only by the European scientists and its circulation were done in mostly through an indirectly top-down process. The knowledge was diffused to the public using native leaders acted as intermediary. The natives who were placed at the bottom of society were treated as if they were inca....................
    (2018-01-01) Haemaphysalis longicornis: Measuring tick burdens on pasture and on sheep.
    Essink, T.
    This research project includes a comparison of two methods to estimate tick burdens of the tick Haemaphysalis longicornis. H.longicornis is the only tick which has considerable importance in New Zealand. It is the only exotic tick which causes production losses in cattle, deer, sheep and other livestock. Furthermore, in New Zealand H. longicornis has been shown to be a competent vector of bovine theileriosis (Theileria orientalis). This gives rise to the need for proper methods to evaluate ticks....................
    (2018-01-01) Influence of Tropical Cyclones on the Statistical Properties of Extreme Waves in the Tropical Indian Ocean
    Nugrahinggil Subasita, .
    In this MSc thesis, the climatology of ocean surface waves in the tropical Indian Ocean is investigated. Specific focus is on the probability distributions of the significant wave height, i.e. the mean height of the 1/3 of the waves over a 10-30 minutes interval, and of the mean wave period. Additionally, the characteristics of extreme waves, with heights that occur only once in e.g. 20 years or 50 years and which are generated by tropical cyclones, are analysed. For this, experiments were cond....................
    (2018-01-01) How Large is the Shadow? Smoothed Analysis of the Simplex Method
    Huiberts, S.
    In this thesis, we show a new improved upper bound on the expected number of edges in the shadow of a random smoothed polyhedron on a two-dimensional plane. We use this bound to give smoothed complexity bounds for the simplex method for linear programming based on existing algorithmic techniques.
    (2018-01-01) Essential oil production in rural Africa
    Appelman, S.N.G.
    The goal of this study is to identify opportunities to reduce the fossil energy use for the steam distillation process of essential oils (EO) in rural Africa. Therefore, renewable energy technologies (RETs) and energy efficiency measures (EEMS) were identified, evaluated and assessed on applicability. As a results, eight technologies were found suitable to achieve this goal, these are: CSP-, biomass- and efficient boiler, an economizer, solar water heating (SWH) system, feedwater condenser, insu....................
    (2018-01-01) Performance evaluation of large-scale hydrological models for different hydro-climatic zones in Australia
    Wagenaar, N.W.
    Climate change will affect volumes and timings of river discharges and will therefore determine the distribution and amount of people experiencing floods and droughts in the future. Therefore, the need for reliable hydrological modeling increases in order to respond to these changes. Modeled output of these models have been compared with observations and it is seen that modeled output is not limited to input forcing only, which results in uncertainty of modeled output. This research aims to eva....................
    (2018-01-01) Remotely sensed and field surveyed early-warning signals of desertification in the Ebro basin, Spain
    Daas, J.H. den
    The Ebro Basin near Zaragoza, Spain is the northern most semi-arid region in Europe with shrubland vegetation, a large water deficit and high grazing pressure in the last century. Early warning signals of desertification in the form of spatial and temporal variation in vegetation cover derived using remote sensing and field measurements were studied. They may provide enough time to act before a critical shift to a barren state induced by overgrazing in semi-arid zones takes place. Vegetation co....................
    (2018-01-01) Action points to advance commercialisation of the Dutch tidal energy sector
    Zuijlen, J.P. van
    Water management has traditionally been focused on water safety, hygiene and agricultural problems, however, given the current need for sustainability in order to combat climate change, the possible production of sustainable energy is a desirable extension of integral water management. Tidal energy is a form of ocean energy which harnesses energy from the tides and has the potential to contribute significantly to sustainable energy solutions in certain coastal regions, thereby reducing carbon em....................
    (2018-01-01) A Pore-Scale Analysis of Colloidal Particle Attachment and Detachment in Porous Media
    Tang, D.W.S.
    The fate of colloidal particles entering soils and groundwater aquifers is an important issue in environmental hydrogeology and many other fields involving porous media. Compared to soluble chemical species, colloidal particles experience different trajectories in porous media, and they cannot be described by continuum hydrodynamics. In addition to physical phenomena such as the clogging of narrow crevices by large particles, colloidal pollutants in the environment are also prone to becoming ads....................
    (2018-01-01) The perfect storm: can sperm whale (Physeter macrocephalus) strandings in the North Sea be linked to storm activity?
    Nielen, J.H.
    In early 2016, 30 male sperm whales (Physeter macrocephalus) stranded along North Sea coasts. Sperm whale mass strandings in the North Sea area have occurred several times over the past century and are relatively well documented. Most strandings occur when sperm whales migrate south from the Norwegian Sea, and enter the shallow North Sea by accident. There are multiple theories regarding the cause of why sperm whales sometimes take the wrong turn into the North Sea ‘trap’. One hypothesis foc....................
    (2018-01-01) A paleolatitude study on Mesozoic rocks from Costa Rica – reconstructing the Caribbean Plate.
    Wiel, E. van der
    Paleomagnetic data-points are important constrains to large scale plate reconstructions. In the case of the Caribbean Plate and its formation in the Panthalassa Ocean there is a lack of Mesozoic constrains. Here we present new paleomagnetic results from Jurassic and Cretaceous oceanic rocks of the Caribbean Plate obtained in northern Costa Rica. Our results show a consistent latitudinal position for the Caribbean lithosphere from 160Ma onwards. With paleolatitudes between the 1° south and 10° ....................
    (2017-01-17) Alcoholgebruik, Alcohol-Specifieke Regels en Impliciete Opvoedcognities
    Rolink, P.
    Introductie: In deze studie is de relatie tussen alcohol-specifieke regels, alcoholgebruik onder jongeren en de modererende rol van impliciete opvoedcognities van ouders omtrent alcohol onderzocht. Methode: Cross-sectionele data zijn verzameld, namelijk vragenlijsten en een impliciete test (Relational Responding Task) onder ouders met adolescente kinderen. In totaal hebben 44 ouders deelgenomen aan het onderzoek met kinderen in de leeftijdscategorie 12-24 jaar. In verband met missende data zijn ....................
    (2017-01-17) Pupil size reflects covert attention unconsciously biased toward regularities
    Lusink, C.L.
    The brain uses statistical learning to extract information from regularities in the environment. To facilitate this process, attention is unconsciously biased towards the regularities. To investigate how attention is biased and how this learning process progresses, we monitored covert attention by using the pupillary light response. We predicted that behavioural data would show statistical learning occurred. In addition, we hypothesised that pupil size reflects unconscious attention biased towar....................
    (2017-01-02) Samenhang tussen ouderlijke warmte/ondersteuning en aandachtvaardigheden van peuters.
    Beeftink, S.
    Het hebben van goede aandachtvaardigheden is cruciaal voor een gezonde ontwikkeling. Het is dan ook van belang te weten welke factoren een rol spelen bij de ontwikkeling van aandachtvaardigheden. In deze cross-sectionele studie is onderzocht of er sprake is van een samenhang tussen ouderlijke warmte/ondersteuning en aandachtvaardigheden van peuters. Participanten waren 104 gezonde Nederlandse peuters (46.2% jongens) in de leeftijd van 18 maanden. Aandachtvaardigheden van peuters zijn gemeten met....................
    (2017-01-01) An estimator for state occupation probabilities in non-Markov multistate models
    Reijbroek, P.W.M.
    In medical research, the progress of a disease can be modelled using multistate models. Quantities of interest are the transition hazard and the state occupation probabilities. In this thesis, we consider estimators of the integrated transition hazard and state occupation probabilities, with the possibility of right-censoring, in multistate models that are not necessarily Markov. We focus on deriving the Nelson-Aalen estimator and the Aalen-Johansen estimator, and show that these are consistent,....................
    (2017-01-01) Accelerating the Mondriaan sparse matrix partitioning package
    Oort, M. van
    We consider a number of modifications to the Mondriaan package for sparse matrix partitioning, with as main goal to improve run times of the software. Two new algorithms are considered, one of which aims at reducing load imbalance to enable Mondriaan to find partitionings with less communication volume, while the other aims at finding solutions with zero communication volume more quickly than Mondriaan currently does. The other modifications include an improved sorting function, an improvement i....................
    (2017-01-01) De militaire psychiatrie in de Krijgsmacht: innovatie en discontinuïteit.
    Loth, J.H.J.
    This paper researches the Dutch military psychological healthcare during warfare, using the implementation of the principles of forward psychiatry as the main subject. These principles are: speed, proximity and positive expectation throughout three conflicts: the decolonization of the Dutch East Indies, the Korean War and the civil war in Lebanon.
    (2017-01-01) De toegevoegde waarde van het Keurmerk Klantgericht Verzekeren
    Jensema, L.
    In dit onderzoek wordt de toegevoegde waarde onderzocht van het Keurmerk Klantgericht Verzekeren op de keuze van jongeren voor verzekeraars en op de begrijpelijkheid van de communicatie-uitingen van verzekeraars. Uit de resultaten blijkt dat de meeste jongeren het keurmerk niet kennen. Daarnaast hebben jongeren niet vaker een voorkeur voor een verzekering met keurmerk. Wel geven jongeren zelf aan het keurmerk belangrijk te vinden en eerder te kiezen voor een verzekeraar met keurmerk. De communic....................
    (2017-01-01) Cognitive impairments and unilateral visuo-spatial neglect: a retrospective study.
    Bonthond, I.
    It is increasingly recognized that neglect symptoms and functional outcome of neglect patients can be exacerbated by cognitive deficits. The current retrospective study aimed to further explore cognitive impairments among a large sample of stroke patients with and without neglect. Among the cognitive functions, information processing speed, memory (i.e. encoding, delayed recall and working memory), attention capacity and visuospatial/constructive skills were assessed. The sample consisted of 160....................
    (2017-01-01) The Geenpeil e-petition: Connectivity, collectivity and the power of professional media in a social media world
    Elden, C. van
    In July 2015 the popular Dutch weblog Geenstijl started off a civil petition movement in favour of a national referendum on the then upcoming association agreement between the European Union and Ukraine, which the Eurosceptic journalists of Geenstijl did not want the Dutch government to sign. Together with the small civil activist organisation Civilian Committee EU, Geenstijl created a website on which people could leave a digital signature to support the referendum request, and employed their o....................
    (2017-01-01) Viewpoint-controlled Navigation in Virtual Reality for Exploratory Image Browsing
    Bolwerk, J.B.W.
    Virtual reality allows users to explore virtual worlds in a close-tonatural way. As the current trend of gaming and tele-presence applications suggests, this has much potential for realistic experiences. But there is more. Not only is the experience realistic, it is also intuitive and thus we aspire to explore the potential of virtual reality for abstract environments. In this thesis we set out to explore the suitability of virtual reality for exploratory image browsing. In particular viewpoint ....................
    (2017-01-01) The Connectome: A Unifying Boundary Object in Neuroscience
    Schipani, V.A.
    In this thesis I have argued that the connectome is a unifying boundary object in neuroscience. In the first chapter, I showed that the dual realness and construction of scientific objects paves the way for the robustness and plasticity of boundary objects, a specific kind of scientific object. These two sets of qualities make up the first and second tier dualities of my thesis argument. The third tier duality, the unity and autonomy of neuroscience’s fields, comes about through the collaborat....................
    (2017-01-01) Children’s exposure to parental alcohol use: An evaluation of the electronic appropriate beverage task Taal
    Schayck, M.T.E. van
    Introduction: Children’s exposure to parental alcohol use could be a determinant for children’s alcohol use in adolescence. Currently, it is unknown whether the electronic Appropriate Beverage Task (eABT) can be used for measuring this determinant. The eABT comprises 18 drawings in which children have to attribute beverages (four alcoholic; eight non-alcoholic) to the persons (N = 72) represented in the drawings. This pilot study examined whether the eABT (1) measures children’s exposure t....................
    (2017-01-01) From lignin to marine biofuel - A market potential and GHG assessment of the most suitable conversion routes in Brazil and Scandinavia.
    Bijleveld, T.M.
    The marine transport is a relatively efficient type of transport per amount of volume tranported. However, it does generate large quantities of greenhouse gas (GHG) emissions due to the large volumes that are transported globally. In 2012, the total GHG emissions from shipping amounted 961 million tonne CO₂-eq, which accounted for 2.5% of the global GHG emissions and this is projected to increase with 50 to 250% by 2050 for the business-as-usual scenario. Needless to say, the marine industry c....................
    (2017-01-01) Synthetic modelling of core-mantle boundary topography
    Rutten, L.W.
    In this study, the resolvability of core-mantle boundary topography was studied using synthetically generated seismic body waves. The full-waveform synthetic seismograms calculated at 2130 stations due to four earthquakes on the equator in the PREM model were compared to the seismograms for an Earth consisting of PREM and the core-mantle boundary (CMB) topography model of Li et al. (1991a) scaled to a peak-to-peak amplitude of 8km. The ray theoretical predictions for travel time delays due to CM....................
    (2017-01-01) Reservoir Properties of Upper Jurassic to Lower Cretaceous Formations in the Northern Dutch Offshore
    Madani, H.
    In the northern Dutch offshore, Upper Jurassic to Lower Cretaceous formations form an important target for hydrocarbon exploration. During the Late Jurassic to Early Cretaceous period, rifting in the Southern North Sea accommodated the deposition of three transgressive mega-sequences, which reflect a general change in energy conditions from proximal towards distal facies. The reservoir sands vary widely in presence, thickness, and reservoir quality, a factor which is still poorly understood. A s....................
    (2017-01-01) Progesterone concentrations before parturition in cows
    Gooijer, J.M.
    The objectives of this study were to evaluate the use of progesterone concentrations in predicting calving time in cows over 265 days of gestation. The incidence of retained fetal membranes after induction to parturition is evaluated as well. Data were collected from the online electronic patient files at the clinic of the Department of Farm Animal Health of the Faculty of Veterinary Medicine in Utrecht. Information was collected about progesterone concentrations, date of insemination, induction....................
    (2017-01-01) Gebruik van Sociale Netwerksites en Welzijn bij Adolescenten: Moderatie-effect van Actieve Media Bemiddeling van Ouders
    Kleine, E. de
    De forse toename van het gebruik van sociale netwerksites (SNS) is een zorgelijk gegeven, gezien de mogelijkheid op gerelateerde negatieve gevolgen. Vanwege het beschermende effect van actieve media bemiddeling door ouders, wordt in de huidige studie het moderatie-effect van actieve media bemiddeling op de relatie tussen het SNS-gebruik en het welzijn van adolescenten onderzocht. Uit onderzoek middels vragenlijsten bij 440 leerlingen (12 tot 19 jaar) blijkt dat er geen sprake is van een signific....................
    (2017-01-01) ‘De invloed van eerder behaalde resultaten en individuele contributies op collectieve efficacy overtuigingen’.
    Bladel, J.D.J. van
    In de huidige studie wordt gekeken naar de mogelijke invloed van verschillende individuele contributies aan het groepstotaal en in het verleden behaalde groepsresultaten op het geloof om als groep een toekomstig positief resultaat te behalen (het principe van collective efficacy). Dit is gedaan aan de hand van een hoge wederzijdse afhankelijkheidstaak waaraan twee participanten als groep deelnemen. De taak betreft een kaartspel waarbij de participanten gelijk aan of hoger moeten scoren dan een v....................
    (2017-01-01) Cognitieve job crafting: De toegevoegde waarde van cognitief craften
    Schutte, G.J.
    This study examines the added value of measuring the cognitive dimension of job crafting relative to the scale developed by Tims et. al. (JD-R crafting; 2011). Although Wrzesniewski and Dutton described three dimensions of job crafting (task, relational and cognitive crafting), Tims et. al. omitted the cognitive dimension in their often-used scale. In 2013 Slemp and Vella-Brodrick developed a new scale based on all three dimensions introduced by Wrzesniewski and Dutton. Data were collected via a....................
    (2017-01-01) Ziekteverzuim en het Job Demand-Control-Support Model: de rol van uitdagende en belemmerende taakeisen.
    Homoed, T.C. van
    Dit artikel doet verslag van een correlationeel onderzoek naar ziekteverzuim en het Job Demand-Control-Support (JD-C-S) model. In het onderzoek werd een mogelijke verfijning van het model onderzocht, waarin onderscheid werd gemaakt tussen belemmerende en uitdagende taakeisen. Zowel belemmerende als uitdagende taakeisen hielden geen verband met ziekteverzuim. De hypotheses die buffereffecten van energiebronnen veronderstelden werden eveneens niet bevestigd. De beperkingen van het onderzoek worden....................
    (2017-01-01) Negative mental imagery in musicians with performance anxiety: an experimental study of the effects of eye movements
    Beek, E. van der
    Musical performance anxiety is not uncommon for vocalists or musicians. It sometimes has major implications for performers as it affects their career in a negative way. The current study aimed to discover whether the use of eye movements would reduce vividness, unpleasantness and emotionality of fear-inducing flash-forwards in musicians. Furthermore, we examined the effects of eye movements on the probability and severity of the image, as well as associated anxiety levels. The latter three are m....................
    (2017-01-01) Zending en overheid: De rol van de Nederlandse overheid met betrekking tot het zendingsbeleid in Nederlands-Indië tussen 1854-1925
    Broerse, P.H.
    In 1854 werd in de Tweede Kamer het regeringsreglement voor de Indonesische archipel gepresenteerd. In dit reglement stonden onder andere artikelen die de zending in de Indonesische kolonie officieel en formeel reguleerden. Voortaan behoorden protestantse zendelingen en katholieke missionarissen een aanvraag te doen bij de Gouverneur van Nederlands-Indië om de zending en missie te bedrijven in een bepaald gebied in Nederlands-Indië. Dit zendingsbeleid had tot doel de protestantse zendingen en ....................
    (2017-01-01) De verloren winnaar. Een analyse naar mannelijk kunstenaarschap in de roman 'James Worthy'.
    Schoeman, A.
    Dit eindwerkstuk besteedt aandacht aan de masculinity studies en het daarbij horende debat over de ‘man in crisis’. Niet de gehele mannelijkheid, maar de hedendaagse mannelijke kunstenaar wordt onderzocht in lijn met deze mannelijke crisis. De primaire bron van onderzoek is de roman James Worthy (2011) van James Worthy. Het personage in deze roman is een mannelijke schrijver met een contradictoire mannelijke identiteit. Twee concepten uit de masculinity studies worden gebruikt om het hoofdpe....................
    (2017-01-01) Preserving and (Re)Presenting: On the Circulation of Dutch WWII Testimonies via New Media in Participatory Memory Projects
    Werkman, K.A.
    More than seventy years after the Second Wold War the eyewitnesses and first generation survivors are dying out and can no longer transmit their stories to future generations. In order to save their testimonies from oblivion various innovative commemoration initiatives are created that often consist of participatory projects using new media. This thesis focuses on three recent Dutch memory projects, Joods Monument and Open Joodse Huizen, Oorlog in mijn Buurt, and Post uit de Vergetelheid in orde....................
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